Cloud-native Bioinformatics: HPC to GCP

Working with a team from the Imperial College in London, we started by reviewing a genomic analysis workflow which is currently running on their HPC cluster. The workflow is a complete analysis for single-cell/nuclei RNA-sequencing data. I started by reviewing the workflow process steps generated by the Nextflow script used to run it.

Next I reviewed the current method of running this workflow by connecting with the team and observing them run this analysis on their HPC cluster. Of note is that the workflow utilizes containerization via Singularity / Docker.